Can You Donate Plasma If You Smoke Weed? CGM Monitors Yes, you can donate blood if you smoke or consume cannabis. The recipient of the blood will not get high, another common MYTH. All donors go through the same health Can You Donate Blood or Plasma if You Use Cannabis? We all know smoking and vaping isn't great for your health. But it doesn't stop you from being a blood or plasma donor. Just make sure to wait one hour after donating