Carnitine Shuttle an overview ScienceDirect Topics The role of carnitine in the transport of mitochondrial long chain Download Scientific Diagram Short Note On Carnitine Shuttle: Fatty acids are oxidized in mitochondria, and synthesized in the cytoplasm. Long chain fatty acids must form an active intermediate, fatty acyl CoA, before being oxidized inside mitochondria. Catherine Carnitine Metabolism and Its Role in Fatty Acid Oxidation Creative Proteomics