Proteolytic processing of lysyl oxidaselike 2 in the extracellular matrix is required for crosslinking of basement membrane collagen IV Journal of Biological Chemistry How GHK Peptide Works Signaling GHK acts as a switch for skin repair: Interacts with adenosine receptors reduces inflammation Activates MAPK ERK, PI3K Akt, TGF pathways Stimulates fibroblasts & keratinocytes boosts collagen, elastin Lysyl oxidase (LOX) mediates intermolecular crosslinks between Download Scientific Diagram Lysine Hydroxylation and Cross Linking of Collagen Springer Nature Link