What is glutathione? Know as the most important antioxidant in the body, glutathione is an essential antioxidant manufactured in all cells, but primarily in the liver. It is essential because it Figure 3 from Glutathione synthesis. Semantic Scholar Glutathione de novo synthesis but not recycling process coordinates with glutamine catabolism to control redox homeostasis and directs murine T cell differentiation eLife Acetaminophen Toxicity: How Genetic Susceptibility Combines with Environmental Factors