VAP Bundle Ventilator Associated Pneumonia Ventilator Associated Pneumonia ( VAP) is a lung infection that occurs in patients who are on mechanical ventilation for more than 48 hours. A VAP bundle is a set of Prevention of Ventilator Associated Pneumonia Guidelines Side By Side Guideline Central Ventilator associated pneumonia: pathobiological heterogeneity and diagnostic challenges Nature Communications 5 Nursing strategies to prevent ventilator associated pneumonia